Rare Ebola strain kills 65 in Congo and Uganda

▼ Summary
– Africa CDC confirmed an Ebola outbreak in DRC’s Ituri province, with a case imported to Kampala, Uganda.
– The DRC has 246 suspected cases and 65 deaths, making it roughly the 10th largest Ebola outbreak.
– This is the 17th DRC outbreak since 1976, but preliminary lab results indicate it is not caused by the Zaire strain.
– The Uganda case involves the Bundibugyo strain, one of four Ebola strains that cause human disease.
– A different strain than Zaire could complicate response, as licensed vaccines and treatments target the Zaire strain.
The Africa Centres for Disease Control and Prevention confirmed an Ebola outbreak on Friday in the northeastern Ituri province of the Democratic Republic of the Congo, with authorities in Uganda later reporting that the virus had crossed the border. One “imported” case has been identified in Kampala, Uganda’s capital.
To date, the DRC has recorded 246 suspected cases and 65 deaths, concentrated mainly in the Mongwalu and Rwampara health zones. Though only now coming to light, this outbreak already ranks as approximately the 10th largest Ebola outbreak since the virus emerged.
This is the 17th Ebola outbreak in the DRC since 1976, but it stands apart from previous ones. Preliminary lab results indicate that the current outbreak is not caused by the Zaire Ebola virus strain, which has been responsible for most past epidemics in the country. Scientists are conducting further genetic sequencing today to identify the exact strain involved.
Four virus strains are known to cause Ebola in humans, and three of them,Zaire, Sudan, and Bundibugyo,have triggered large-scale outbreaks. According to an early Reuters report from Uganda, officials there stated that the case involves the Bundibugyo strain.
This shift in strain introduces complications, according to Jean-Jacques Muyembe, the Congolese virologist who co-discovered Ebola and leads the National Institute for Biomedical Research in Kinshasa. He told Reuters that since existing licensed vaccines and treatments were developed specifically against the Zaire strain, a different strain could undermine response efforts.
(Source: Ars Technica)
