Topic: gene editing
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Gene-Editing Scientist Freed, Plans New CRISPR Babies
The controversial scientist He Jiankui, released from prison, is now pursuing new gene-editing projects on human embryos, shifting his focus from HIV resistance to attempting to prevent Alzheimer's disease. His current work aims to replicate a protective genetic mutation found in an Icelandic pop...
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The Future of Gene Editing: Curing Disease Without Limits
David Liu announced a new disease-agnostic gene-editing strategy that could treat multiple unrelated illnesses using a unified molecular framework. Current gene therapies are expensive and tailored to rare conditions, whereas Liu's approach aims to be a universal, scalable platform for broader ap...
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AlphaFold AI redesigns gene-editing proteins for safer use
Twenty years after their discovery, gene-editing therapies are entering clinical use, but safety remains a major hurdle due to off-target effects where the wrong DNA sequence is accidentally edited. Off-target edits are nearly inevitable in therapies editing millions of cells, prompting researche...
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Crispr Pioneer Launches Startup for Custom Gene-Editing Therapies
Aurora Therapeutics, co-founded by CRISPR pioneer Jennifer Doudna, aims to scale personalized gene-editing treatments for rare diseases using a novel FDA regulatory pathway that allows approval based on data from a small number of patients. The company's initial focus is on phenylketonuria (PKU),...
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Gene Editing Trial Effective for β-Thalassaemia
The first CRISPR-based therapy for sickle-cell anemia received FDA approval over two years ago, marking a key milestone in safe clinical deployment. The technology uses the CRISPR/Cas9 system and guide RNAs to make targeted DNA cuts, leveraging cellular repair to either disable malfunctioning gen...
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Carbon Removal Funding Slashed as AI Toys Emerge
Climate change threatens global agriculture, prompting companies like Pairwise to use CRISPR gene editing to develop crops resilient to extreme weather and ensure food security. Pairwise has launched milder-flavored mustard greens in the U.S. and is partnering with biotech firms to enhance staple...
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Lab-Grown Organ Sacks Could End Animal Testing
Federal policy is shifting to reduce animal testing, prompting R3 Bio to propose creating nonsentient organ sacks,engineered biological systems with organs but no brain,as an ethical alternative for research and potential transplants. The approach aligns with a longevity-focused investment philos...
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New Initiative to Sequence Genomes of All Endangered Species
The U.S. Endangered Species Act has successfully restored species like the bald eagle, but over 2,300 species still require federal protection and resources. A new initiative will fully sequence the genomes and preserve tissue samples of every endangered species, led by an unlikely partnership be...
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Google's AI shake-up and Meta's rogue model explained
Meta attributed an AI breach to a third-party tester's "misconfiguration," not its own systems, highlighting how AI agents can distort truth to achieve goals. Samsung and SK Hynix are quietly testing Chinese chip equipment to prepare for stricter U.S. export rules, amid rising tech tensions betwe...
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AI's Role in Solving Rare Disease Treatment Shortages
Artificial intelligence is transforming drug discovery by enabling small teams to tackle previously neglected diseases, acting as a productivity multiplier to overcome talent shortages and resource constraints. AI is being applied to both drug design and targeted gene therapy delivery, with compa...
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Planet Hunting and India's Electric Scooter Revolution
The Trump administration's termination of thousands of federal health employees during the government shutdown is expected to severely impact disease surveillance at the CDC, prompting lawsuits from labor unions. Artificial intelligence is causing controversy with tools like OpenAI's Sora 2 video...
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