Salmon Sperm: The Latest Skincare Trend Explained

▼ Summary
– Rejuran is a Korean skincare serum featuring PDRN, a trendy ingredient derived from salmon sperm, which is marketed to rejuvenate skin and reduce wrinkles.
– Cosmetic chemist Victoria Fu explains that while injectable PDRN has medical research for wound healing, evidence for topical PDRN’s effectiveness is very limited and it cannot substitute for injectable procedures.
– The popularity of PDRN in skincare grew from expensive, painful facial injections in South Korea, promoted by celebrities, and has since expanded into more accessible topical products like serums.
– Marketing terms like “clinically proven” and “science-backed” are often misleading, and plant-based PDRN alternatives exist but may not be equivalent to the clinically studied material.
– Experts advise that skincare fundamentals like sunscreen and retinoids are more impactful, and while PDRN is likely harmless, consumers should be skeptical of exaggerated claims and focus on proven routines.
The world of skincare constantly introduces new ingredients promising revolutionary results, and the latest buzz centers on PDRN, an extract derived from salmon sperm. This compound, polydeoxyribonucleotide, is being hailed in serums and treatments for its supposed ability to rejuvenate skin, boost collagen, and smooth wrinkles. While its origins might raise eyebrows, the science behind it stems from medical research into wound healing, though its effectiveness in a topical bottle is a different story entirely.
Scrolling through social media, it’s easy to feel a historical sense of déjà vu. The lengths people go for youthful skin, from vintage tales of blood baths to modern viral trends like snail slime and bird poop facials, show our enduring vanity. Now, videos showcase influencers with dewy complexions praising clear liquids from sleek bottles. They claim this ingredient, with molecules 670 times smaller than pores, offers unparalleled absorption and transformative effects. It’s a compelling narrative, especially when it promises medical-grade benefits without a doctor’s visit.
“PDRN is essentially a DNA fragment,” explains cosmetic chemist Victoria Fu. “Earlier versions came from human placenta, but salmon sperm PDRN is now the industry standard.” The ingredient’s journey into beauty began in medicine, where injected forms were studied for healing stubborn wounds like diabetic foot ulcers. Injectable treatments can deliver ingredients deep into the skin’s structure for significant changes, which is why procedures often outperform topical products. However, these injectables are not FDA-approved for cosmetic use in the United States.
Online, PDRN first gained attention through videos of “salmon sperm facials” in South Korea. Viewers watched as doctors injected the solution, creating a temporarily swollen, pin-cushioned face, followed by boasts of a radiant glow. The trend exploded when celebrities publicly endorsed it, paving the way for companies like Rejuran to launch a topical serum. Suddenly, for about $52 a bottle, anyone could try it, bypassing the $500+ facial and the long recovery.
This marketing is powerful. Even with a skeptical eye, the allure of science-adjacent claims is hard to resist. Many consumers, hoping for a non-invasive miracle, are drawn to phrases like “clinically proven” and “patented science.” Yet, experts urge caution. “A serum cannot be a non-invasive substitute for an injectable procedure,” Fu states. The delivery method is crucial; injectables place ingredients directly into tissue at concentrations and depths topicals simply cannot reach.
Despite the limited evidence for over-the-counter versions, the skincare industry continues to embrace the trend. Brands now offer plant-based alternatives, claiming ginseng or rose-derived PDRN provides vegan-friendly benefits. “Plant-based PDRN is a marketing gray area,” Fu notes. “It may contain DNA fragments, but that doesn’t automatically equal the material studied clinically. Source, purity, and molecular size all dramatically affect performance.”
For the average consumer, PDRN is considered a mild active unlikely to cause irritation, making it a safe option for experimentation. However, it should not replace cornerstone products. The fundamentals, sunscreen, moisturizer, and proven actives like retinoids, remain the true workhorses of any effective routine. The primary risk with trendy ingredients like PDRN is financial, playing on the desire for quick fixes over patience and consistency.
Navigating the noise requires a critical eye. Look for quantifiable data from brands, such as specific percentage improvements in elasticity, rather than vague consumer testimonials. Be wary of before-and-after photos that can be manipulated with lighting and angles. As Fu advises, avoid knee-jerk reactions to trends and stay focused on a solid, researched regimen.
After personal experimentation with a salmon-based serum, the results are subtle at best, perhaps a slight glow or minor improvement in a scar. The experience underscores a broader truth: informed choices matter. Knowing that dramatic results were unlikely, the trial was a conscious, low-risk diversion. The real skincare commitment lies in those daily, unglamorous fundamentals that truly protect and improve skin over time. In the end, while trying the latest potion might be harmless fun, lasting beauty relies on proven science and disciplined care.
(Source: The Verge)


